Targeted nutritional support for blood sugar balance
Special, targeted supplemental support for individuals with undesirable blood sugar levels who may have special dietary needs for higher amounts of important micronutrients. Formulated by doctors Johnathan Wright and Alan Gaby.
GlucoBalance is a potent multi vitamin and mineral that offers a number of benefits.
- Contains nutrients in suitable amounts to help balance blood glucose levels when faced with a busy professional life, and stresses - which would otherwise contribute to imbalances in blood glucose.
- Contains nutrients that support muscle and encourage fat metabolism.
- Contains good levels of antioxidants including Vitamin E and Selenium that protect cells from free radical damage.
- Contains a uniquely high amount of biotin – 3000 mcg - which is essential for the first step on converting carbohydrates into energy.
- Contains good levels of B vitamins that support energy and the nervous system.
- Contains vitamins that support adrenal function including B vitamins and Vitamin C.
- GlucoBalance can help to reduce an excess appetite.
- Glucobalance has been clinically trialled with Flax Seed Oil and found to lower blood triglyceride levels, and cholesterol whilst improving HDL (good) cholesterol.
|Vitamin A (as retinyl acetate)||5000 IU||100%|
|Vitamin C (as calcium ascorbate and ascorbic acid)||500mg||833%|
|Vitamin D (as cholecalciferol)||100 IU||25%|
|Vitamin E (as d-alpha tocopheryl acetate)||400 IU||1333%|
|Thiamin (B1) (as thiamin mononitrate)||50mg||3333%|
|Niacin (as niacinamide and niacin)||150mg||750%|
|Vitamin B6 (as pyridoxine hydrochloride)||30mg||1500%|
|Folate (as calcium folinate)||800mcg||200%|
|Vitamin B12 (as methylcobalamin)||50mcg||833%|
|Pantothenic Acid (as calcium pantothenate)||100mg||1000%|
|Calcium (as ascorbate, citrate and carbonate)||200mg||20%|
|Magnesium (as aspartate, citrate and oxide)||400mg||100%|
|Zinc (as zinc picolinate and zinc citrate)||30mg||200%|
|Selenium (as selenomethionine)||150mcg||214%|
|Copper (as copper gluconate)||2mg||100%|
|Manganese (as manganese citrate)||20mg||1000%|
|Chromium (as chromium aspartate)||1000mcg||833%|
|Potassium (as potassium aspartate)||99mg||3%|
|Vanadium (as vanadium aspartate)||20mcg||*|
* RDA not established
Ingredients: Capsule Shell (Gelatin and wWater) and Magnesium Stearate (Vegetable Source).
This product is gluten and dairy free.
WARNING: If you are taking Diabetes medications, do not use this product without medical supervision.
Directions for use
Six (6) capsules each day, with meal, as a foodsupplement. Do not exceed the recommended daily dose. Not to be used as a substitute for a varied diet.
WHY TAKE SUPPLEMENTS TO SUPPORT BLOOD GLUCOSE BALANCE?
Effective Regulation of blood glucose has implications for health. Even mild disruptions of glucose homeostasis can have adverse consequences. Chronic diabetes may result in cardiovascular disease, neuropathy, blindness or renal failure. Hypoglycemia (also called reactive hypoglycemia or dysinsulinism), though not general associated with the organ damage seen in diabetes, can be responsible for a number of troublesome physical and psychological symptoms.
The human body possesses a complex set of checks and balances to maintain blood glucose concentrations within a narrow range. Blood sugar control is influenced by the pituitary, thyroid and adrenal glands, as well as by the pancreas, liver, kidney and even skeletal muscle.
Glucose homeostasis also depends on the presence of a wide range of micronutrients. In the typical American diet, high in refined and processed foods, many of these micronutrients are in short supply. In addition, some individuals with blood sugar disorders may have a special dietary need for higher amounts of one or more micronutrients.
The following nutrients are particularly important when considering blood sugar disorders:
The effect of chromium on glucose metabolism apparently requires its conversion to glucose tolerance factor (GTF), a low-molecular-weight compound that contains chromium, niacin (nicotinic acid), glycine, glutamic acid and cysteine. GTF, has been shown to potentiate the action of insulin at the cellular level. 
Tissue chromium levels were found to decline with age in Americans . In other studies, including one by the U.S. Department of Agriculture, more than 50% of people consumed less than the lower level of chromium recommended by the National Academy of Sciences, Nutritional Research Council.   Chromium aspartate is a well-utilised form of supplemental chromium being solubilised at a wide range of ph. The amounts of chromium used in most clinical trials (*150 to 200 ug/day) are apparently inadequate for some patients, even when more efficient Chromium compounds are used. Larger amounts of chromium, such as 500 to 1000 ug/day, have often had a greater benefit. 
NIACIN AND NIACINAMIDE
As a component of glucose tolerance factor, niacin plays an important role in carbohydrate metabolism. Many refined foods consumed by Americans are depleted of niacin. Grains and other foods that are “enriched” usually contain added niacinamide, which apparently cannot be converted by the human body into niacin. In addition, many vitamin supplements contain niacinamide, rather than niacin. Although niacinamide is capable of performing most of the functions of vitamin B3, a small amount of niacin seems to be necessary for the synthesis of GTF.  Both niacin and niacinamide may also be important for blood sugar control through a mechanism unrelated to GTF. As precursors to NAD, which is an important metabolite concerned with intracellular energy production, niacin and niacinamide may prevent the depletion of NAD in pancreatic B cells.
The initial step in glucose utilisation by the cell is its phosphorylation, mediated by the biotin-dependent enzyme hepatic glucokinase. Thus adequate biotin intake is required to initiate intracellular glucose into the cell. 
Biotin may also play a role in stabilising blood sugar levels through biotin-dependent enzymes acetyl Co A carboxylase and pyruvate carboxylase.  Thus biotin deficiency should be avoided in those with blood sugar disorders.
PYRIDOXINE (VITAMIN B6)
Because the typical American & UK diets contain only about half of the RDA (2 mg/day) for copper (9,36), deficiency of this mineral may be common. Copper is involved with insulin binding, and copper deficiency in mammals may be reflected in increased glycosylated hemoglobin, indicative of chronically raised blood sugar levels. 
Dietary surveys have shown that 80-85% of American women consume less than the RDA for the mineral.  Daily magnesium intake in two other studies was only about two-thirds of the RDA.    This may be particularly relevant in diabetics, where magnesium deficiency is thought to play a role in the development of insulin resistance. (14) Serum magnesium has been found to be significantly lower in many diabetics , therefore, it is reasonable to make sure that diabetics have adequate dietary intake of magnesium. Low magnesium levels may also be associated with hypoglycemia. 
Zinc is involved both with insulin synthesis by pancreatic B cells  and insulin binding to liver and adipose tissue cells.   People with zinc deficiency may have significantly higher glucose levels and lower insulin levels than similar patients without zinc deficiency. 
VITAMIN C (ASCORBIC ACID)
Ascorbic acid levels may be lower in diabetics than controls  and patients with inadequate ascorbic acid levels may be found to have abnormal blood sugar curves.  In addition, ascorbic acid may compete with glucose for transport across cell membranes,  so that in hyperglycemia, ascorbic acid transport into the cell may be inhibited. 
Ascorbic acid deficiency may allow sorbitol to accumulate in erythrocytes, which may pre-dispose diabetics to certain types of end-organ damage.  Care should be taken to ensure that those with blood sugar abnormalities have adequate ascorbic acid intake.
Manganese is a cofactor for certain enzymes involved in the intermediary metabolism of carbohydrates. In addition, the concentration of manganese in the pancreas is approximately ten times higher than in other organs. 
Both B12 and folate are involved in a number of different steps in carbohydrate metabolism and the incidence of B12 deficiency was significantly greater in a series of diabetics than in the general population.  Folate is involved with gluconeogenesis as a cofactor with key enzymes in the liver and small intestine.  Deficiency of either B12 or folate is to be avoided in those with blood sugar abnormalities.
VITAMIN B1 (THIAMINE)
Central to carbohydrate metabolism and Krebs Cycle function is adequate thiamine levels, and diabetics are more often deficient in thiamine.  Care should be taken to ensure that thiamine intake is adequate in those with diabetes and hypoglycemia.
Carnitine is involved as part of a vital transport mechanism of fat metabolism in which fat enters energy production pathway. Carnitine supplementation may be considered in those with blood sugar abnormalities.
Vanadate is an oxidised form of vanadium. Due to possible insulinotropic effects of vanadate , inadequate amounts of this trace mineral is undesirable in those blood sugar abnormalities.
VITAMIN E AND SELENIUM
Vitamin E and selenium are essential nutritional factors which act as antioxidants and may be involved in glucose balance.   As many complications associated with diabetes may be related to excess free radical activity, prudence demands that adequate selenium and vitamin E be supplied in the diabetic diet.
Eat regular meals containing high biological value proteins and consume whole, fresh foods, and minimise all forms of refined sugar and carbohydrates. Drink plenty of fresh water. Chew food well, and relax when eating. Take some form of exercise daily.
CAUTIONS & CONTRAINDICATIONS
If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.
If diabetic, consult your doctor before use.
Keep in a cool, dry place, tightly capped and stored out of reach of children.
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